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KMID : 0363420210350020001
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Journal of Korean Oriental Pediatrics
2021 Volume.35 No. 2 p.1 ~ p.10
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A Systematic Review of Economic Analysis on Idiopathic Short Stature
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Lee Bo-Ram
Kwon Chan-Young
Jang Soo-Bin
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Abstract
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Objectives: We aimed to examine health-related economic analysis of available interventions on idiopathic short stature (ISS).
Methods: Eight studies were reviewed from English, Korean, and Chinese databases which were published up to December 24, 2020. Effectiveness, utility, and cost data were extracted from the studies and descriptive analysis of the individual studies was conducted
Results: Five studies were chosen. In the two economic evaluation studies, the incremental cost-effectiveness ratio (ICER) of growth hormone (GH) treatment was presented by performing cost-effectiveness analysis based on the deterministic decision tree approach for the GH and untreated group. Final adult height and direct medical costs were analyzed as effectiveness and cost outcomes. In 1 review article, an ICER of GH was presented based on systematic review on the effects of the GH treatment. In the two clinical trials, the effectiveness and cost of the 12 months Oriental medicine combination treatment were presented in comparison with the GH treatment alone. There were no literatures that provided utility data of available intervention on ISS.
Conclusions: The results of this study will be used as basic data for the economic analysis of Oriental medicine treatment on ISS in the future.
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KEYWORD
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Idiopathic short stature, Economic evaluation, Cost-effectiveness analysis, Systematic review
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